The formula

Whole-number multiplier
n = molar mass / empirical formula mass
Building the molecular formula
molecular formula = (empirical formula) × n
Empirical formula mass
EFM = Σ (atoms in the empirical formula × atomic mass)

What the symbols mean

SymbolMeaningUnit
nWhole-number multiplier relating the two formulasdimensionless integer
molar massMeasured molar mass of the compoundg/mol
EFMEmpirical formula mass, the molar mass of one empirical formula unitg/mol
atomic massStandard atomic weight from the periodic tableg/mol

When it applies

  • You already have the empirical formula and an experimentally measured molar mass. Composition data alone can never reach the molecular formula.
  • The multiplier has to come out as a whole number within rounding. A value like 2.5 means the empirical formula was wrong, not that the molecule has half an atom.
  • Ionic compounds have formula units rather than molecules, so sodium chloride is written NaCl and stops at the empirical formula.
  • Different compounds can share one empirical formula. CH₂O covers formaldehyde, acetic acid and glucose, and only the molar mass separates them.

Worked example

Problem. A compound has the empirical formula CH₂O and a measured molar mass of 180.16 g/mol. What is its molecular formula?

  1. Work out the empirical formula mass: C + 2H + O = 12.011 + 2(1.008) + 15.999 = 30.026 g/mol.
  2. Divide the measured molar mass by it: n = 180.16 / 30.026 = 6.000.
  3. That is a whole number, so multiply every subscript in CH₂O by 6: C₆H₁₂O₆.
  4. Check the result: 6(12.011) + 12(1.008) + 6(15.999) = 180.16 g/mol, which matches the measured value.

Answer. C₆H₁₂O₆, six times the empirical formula, which is the formula of glucose.

Common mistakes

  • Dividing the empirical formula mass by the molar mass. The measured molar mass is the larger number and belongs on top.
  • Rounding a multiplier of 2.5 to 3 to force a whole number, instead of going back and rechecking the empirical formula.
  • Multiplying only the first subscript. Every subscript in the empirical formula is multiplied by n.
  • Assuming the molecular formula is always different. When n comes out as 1 the two formulas are identical, as they are for water and for ammonia.

Related formulas

Sources